Critical Care Reviews Newsletter Newsletter 688  |  February 16th, 2025 Welcome to the 688th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. The highlights of this week's edition are randomised controlled trials on early hydrocortisone versus placebo in neonatal shock & intravenous nerinetide for acute cerebral ischaemia; systematic reviews and meta analyses on antibiotic prophylaxis in polytrauma patients & high-flow nasal oxygen therapy in patients with hypercapnic...