Critical Care Reviews Newsletter

Welcome to the 695th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.

The highlights of this week's edition are randomised controlled trials on early intra-aortic balloon support for heart failure-related cardiogenic shock & flexible-tip bougie vs. stylet for tracheal intubation with a hyperangulated videolaryngoscope in critical care; systematic reviews and meta analyses on the association between energy delivery and outcomes in adult critically ill patients diagnosed with or at risk of malnutrition & remote ischaemic preconditioning and survival in noncardiac surgery; and observational studies on metabolic septic shock sub-phenotypes & cardiac arrest during long-distance running races.

There are also guidelines on fluid therapy in adult critically ill patients & diagnosis of adult ARDS and non-mechanical ventilation treatment in China; narrative reviews on high-resolution multimodality neuromonitoring for traumatic brain injury management & vasoactive agents in cardiogenic shock related to myocardial infarction and acute decompensated heart failure; editorials on vasoplegia in cardiac surgery & evidence, implementation, and challenges in mechanical ventilation; and commentaries on clinician prediction of hyperinflammatory ARDS subphenotypes & what Is the new research in pediatric ARDS since the 2023 consensus conference?. 

If you only have time to read one review article this week, try this one on sepsis subphenotypes, theragnostics and personalized sepsis care.

Critical Care Reviews Meeting 2025

The provisional scheduling for the Critical Care Reviews Meeting 2025 is now available. Twelve of the hottest trial results to be presented this year are on the programme. One-day, two-day and three-day in-person registrations are available. If you can't make it to Titanic Belfast, join us online, either as a virtual delegate to claim CPD/CME points, and support this not-for-profit meeting, or simply watch the free livestream. 

Wednesday, June 11th

• TARGET Protein - Augmented Administration of Enteral Protein to Critically Ill Adults
• TTM2 - Biomarkers of Brain Injury after Cardiac Arrest
• ENCOMPASS - Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship 
• RESCUE 3 - Temporary Transvenous Diaphragm Pacing versus Standard of Care for Weaning From Mechanical Ventilation 

Thursday, June 12th

• UK-ROXS - Conservative Oxygenation in Critically ill Mechanically Ventilated Patients
• NOTACS - Nasal High-Flow Oxygen Therapy after Cardiac Surgery 
• ANH - Acute normovolemic hemodilution in cardiac surgery patients
• FLUID - Crystalloid FLUID Choices for Resuscitation of Hospital Patients 

Friday, June 13th

• GASTROSAM - Gastroenteritis Rehydration Of children with Severe Acute Malnutrition
• PRINCE - Ischaemic Preconditioning in Non Cardiac Surgery 
• PROMIZING - Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation 
• INdex - CT-Perfusion and CT-Angiography for Death by Neurologic Criteria
• John Hinds Lecture - "Ukuthola ubuhle"