Dr Padmanabhan Ramnarayan, MD (Ram) is Reader in Paediatric Critical Care at Imperial College and Consultant in Paediatric Intensive Care at St Mary's Hospital in London. He has a long-standing research interest in the epidemiology of paediatric critical illness (including the effects of centralisation of specialist care), provision of non-invasive respiratory support, and pragmatic clinical trials in critical care. He is currently leading the FIRST-ABC master protocol, the largest clinical trial comparing nasal high-flow with continuous positive airway pressure in acutely ill children (step-up RCT) and following extubation (step-down RCT). He is also a co-investigator on some of the ongoing pragmatic clinical trials in paediatric critical care (Oxy-PICU, PRESSURE) and has received over £6 million in NIHR funding over the past 3 years. In the past, Ram has led the DEPICT Study (NIHR HSDR) and been a co-investigator on the CATCH trial (NIHR HTA).

Ram has published extensively (>100 peer-reviewed articles), written several book chapters and lectures regularly at national and international scientific meetings. He regularly reviews articles for high-impact journals including the New England Journal of Medicine, the Lancet and Pediatric Critical Care Medicine. Ram is the current Chair of the Paediatric Critical Care Society Study Group (PCCS-SG), the national paediatric critical care research group, and holds national leadership roles in the NHS England Clinical Reference Group and the Paediatric Intensive Care Audit Network (PICANet).

Twitter:  @pic_pram

Dr Richards-Belle has an academic background in Psychology (University of Southampton) and over 8 years’ experience working on and managing large-scale randomised clinical trials and observational cohort studies in the field of critical care at the Intensive Care National Audit & Research Centre (ICNARC). Studies included: the evaluation of a complex psychological intervention aimed at preventing the development of PTSD symptoms in patients recovering from critical illness and epidemiological studies exploring the first epidemic wave of COVID-19 in critical care.

Twitter: @Alvin_R_B

Dr. Horvat is board-certified in Pediatrics, Pediatric Critical Care Medicine and Clinical Informatics. His academic interests focus on the National Academy of Medicine's Learning Health System concept. He is currently funded by a K23 career development award (1K23HD099331-01A1) titled "A Learning Health System Approach to Precision Sedation and Analgesia in Critically Ill Children" from the National Institute for Child Health and Human Development (NICHD). In his current work, Dr. Horvat aims to utilize a combination of electronic health record-derived datasets, pharmaco kinetic models and pharmacogenomic insights to develop advanced clinical decision support tools to help refine the use of potent sedatives and analgesic medications in the pediatric intensive care unit.

He also serves a number of other roles in clinical informatics, including leading the development of informatics-integrated multidisciplinary workflows for detecting and treating pediatric sepsis, spearheading the creation of artificial intelligence tools for predicting inpatient pediatric deterioration events, and helping to deploy randomized, embedded, multifactorial, adaptive, platform (REMAP) trials across the UPMC system.

Dr. Martha A. Q. Curley is the Ruth M. Colket Endowed Chair in Pediatric Nursing at the Children’s Hospital of Philadelphia and Professor at the University of Pennsylvania School of Nursing. She also holds a joint appointment in Anesthesia and Critical Care Medicine at the University’s Perelman School of Medicine. Her research, funded in the United States by the NHLBI, NINR and NICHD, has focused on nurse-implemented interventionsin pediatric critical care.Over several decades, her studies have informed the practice of caring for critically-ill pediatric patients with acute respiratory failureand haveilluminated relationship-based care when partnering with parents-of-critically-ill childrenThis year Marthawill receive Society of Critical Care Medicine’s, Drs. Vidyasagar and Nagamani Dharmapuri Award for sustained exemplary and pioneering achievements in the care of critically ill and injured infants and children.In addition, Dr.Curley has led the development and dissemination ofcore metrics in the field of pediatrics; for example, the State Behavioral Scale(SBS), the Withdrawal Assessment Tool (WAT-1), individualized numeric rating scale (INRS) and the Braden QDscale. Dr. Curley is a member of the NationalAcademy of Medicine (IOM) and a fellow in the American Academy of Nursing(FAAN). Martha received her diploma in nursing from Springfield Hospital School of Nursing, her BSfrom the University of Massachusetts at Amherst,

Twitter:  @maqcurley

Prof David Harrison graduated from the University of Cambridge with an MA in mathematics and a PhD in mathematical modelling of disease progression. He has worked for ICNARC since 2002. David is a Fellow of the Royal Statistical Society and an Honorary Professor in the Medical Statistics Unit of the London School of Hygiene & Tropical Medicine.