General
General Management
- Slattery. Acute kidney injury in the critically unwell patient. Anaesth Intensive Care Med 2024;25(1):56-62
- Pickkers. Acute kidney injury in the critically ill: an updated review on pathophysiology and management. Intensive Care Med 2021;47(8):835-850
- Kellum. Acute kidney injury. Nat Rev Dis Primers 2021;7:52
Background
Pathophysiology
- Baker. Adding insult to injury: the spectrum of tubulointerstitial responses in acute kidney injury. J Clin Invest 2025;135(6):e188358
- Makhija. Haemodynamic predisposition to acute kidney injury: Shadow and light! J Anaesthesiol Clin Pharmacol 2022;38(3):353–359
- Hall. Metabolic mechanisms of acute proximal tubular injury. Pflugers Arch - Eur J Physiol 2022;epublished May 14th
- Ho. The Proximal Tubule as the Pathogenic and Therapeutic Target in Acute Kidney Injury. Nephron 2022;epublished March 10th
Organ Crosstalk
Venous Congestion
Aortic Valve Intervention
Progression to CKD
- Pan. Unveiling the enigma of acute kidney disease: predicting prognosis, exploring interventions, and embracing a multidisciplinary approach. Kidney Res Clin Pract 2024;43(4):406-416
- Wang. From AKI to CKD: Maladaptive Repair and the Underlying Mechanisms. Int J Mol Sci 2022;23(18):10880
- Levey. Defining AKD: The Spectrum of AKI, AKD, and CKD. Nephron 2021;epublished June 24th
- Gameiro. Long-term consequences of acute kidney injury: a narrative review. Clin Kid J 2021;14(3):789–804
Renal Functional Reserve
Conditions
Sepsis
- Legrand. Sepsis-associated acute kidney injury: recent advances in enrichment strategies, sub-phenotyping and clinical trials. Crit Care 2024;28(1):92
- Kounatidis. Sepsis-Associated Acute Kidney Injury: Where Are We Now? Medicina 2024;60:434
- Wang. Sepsis-Associated Acute Kidney Injury. Intensive Care Res 2023;3:251–258
- He. Sepsis-induced AKI: From pathogenesis to therapeutic approaches. Front Pharmacol 2022;epublished September 15th
- Ow. Targeting Oxidative Stress in Septic Acute Kidney Injury: From Theory to Practice. J Clin Med 2021;10(17):3798
- Ludes. Role of Damage-Associated Molecular Patterns in Septic Acute Kidney Injury, From Injury to Recovery. Front Immunol 2021;12:606622
Drug-Induced
- Vodovar. Amoxicillin crystalluria and Amoxicillin-induced crystal nephropathy: a narrative review. Kidney Int 2024;epublished October 28th
- Karimzadeh. Moving toward a contemporary classification of drug-induced kidney disease. Crit Care 2023;27(1):435
- Campbell. Overview of Antibiotic-Induced Nephrotoxicity. Kidney Int Rep 2023;8(11):2211–2225
- Antognini. Detection, Monitoring, and Mitigation of Drug-Induced Nephrotoxicity: A Pragmatic Approach. Ther Innov Regul Sci 2023;epublished December 18th
- Campbell. Overview of Antibiotic-Induced Nephrotoxicity. Kidney Int Rep 2023;8(11):2211–2225
- Perazella. Drug-Induced Acute Kidney Injury. Clin J Am Soc Nephrol 2022;17(8):1220-1233
- Sanchez-Alamo. Facing the Challenge of Drug-Induced Acute Interstitial Nephritis. Nephron 2022;epublished July 13th
- Kan. Vancomycin-Associated Acute Kidney Injury: A Narrative Review from Pathophysiology to Clinical Application. Int J Mol Sci 2022;;23(4):2052
Liver Disease
- Regner. Management of AKI in Patients with Cirrhosis. Curr Treat Options Gastro 2022;epublished September 15th
- Cullaro. Acute Kidney Injury in Patients with Liver Disease. Clin J Am Soc Nephrol 2022;epublished July 28th
- Platt. Literature review of the mechanisms of acute kidney injury secondary to acute liver injury. World J Nephrol 2022;11(1):13-29
Cardiogenic Shock
Cardiac Surgery
- Kamla. Kidney Injury Following Cardiac Surgery: A Review of Our Current Understanding. Am J Cardiovasc Drugs 2025;epublished January 12th
- Yang. Cardiopulmonary bypass associated acute kidney injury: better understanding and better prevention. Ren Fail 2024;46(1):2331062
- Casanova. Diagnosis of Cardiac Surgery-Associated Acute Kidney Injury: State of the Art and Perspectives. J Clin Med 2022;11(15):4576
- Schurle. CSA-AKI: Incidence, Epidemiology, Clinical Outcomes, and Economic Impact. J Clin Med 2021;10(24):5746
- Ostermann. Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI. J Clin Med 2021;10(22):5285
- Massoth. Diagnosis of Cardiac Surgery-Associated Acute Kidney Injury. J Clin Med 2021;10(16):3664
Contrast-Induced
- Sůva. Contrast-induced acute kidney injury and its contemporary prevention. Front Cardiovasc Med 2022;9:1073072
- Chaudhari. Contrast-Induced Acute Kidney Injury: Evidence in Support of Its Existence and a Review of Its Pathogenesis and Management. Int J Nephrol Renovasc Dis 2022;15:253—266
- Cashion. Radiographic Contrast Media and the Kidney. Clin J Am Soc Clin Nephrol 2022;2022;17(8):1234-1242
- Mandurino-Mirizzi. Contrast-Associated Acute Kidney Injury. J Clin Med 2022;11(8):2167
- Li. Contrast-Associated Acute Kidney Injury: Advances and Challenges. Int J Gen Med 2022;15:1537-1546
Perioperative
- Douville. Perioperative Acute Kidney Injury: Diagnosis, Prediction, Prevention, and Treatment. Anesthesiology 2024;epublished November 11th
- Zeng. Future Directions in Optimizing Anesthesia to Reduce Perioperative Acute Kidney Injury. Am J Nephrol 2023;54(9-10):434–450
- Boyer. Postoperative AKI. Clin J Am Soc Nephrol 2022;epublished June 16th
- Franzén. Anesthesia and the renal sympathetic nervous system in perioperative AKI. Semin Nephrol 2022;epublished November 17th
- Billings. The incidence, risk, presentation, pathophysiology, treatment, and effects of perioperative acute kidney injury. Can J Anaesth 2021;68(3):409–422
Traumatic Brain Injury
- Husain-Syed. Acute kidney injury in neurocritical care. Crit Care 2023;27(1):341
- De Vlieger. Kidney Dysfunction After Traumatic Brain Injury: Pathophysiology and General Management. Neurocrit Care 2022;epublished November 2nd
- Pesonen. Acute kidney injury after brain injury: does it exist? Minerva Anestesiologica 2021;87(7):823-7
Malignancy
Renal Transplantation
Liver Transplantation
Hematopoietic Cell Transplantation
ECMO
- Foti. Acute Kidney Injury and Extracorporeal Membrane Oxygenation: Review on Multiple Organ Support Options, Int J Nephrol Renovasc Dis 2021;14:321-329
- Selewski. Continuous renal replacement therapy in patients treated with extracorporeal membrane oxygenation. Seminars in Dialysis 2021;epublished March 25th
Malaria
Wasp Sting
Obstructive Uropathy
Immune Checkpoint Inhibitor
Iatrogenic AKI
Ventilator-Induced AKI
Complications
Uraemic Encephalopathy
Transition to CKD
Monitoring & Investigations
Biomarkers
- Yang. Advances in the diagnosis of early biomarkers for acute kidney injury: a literature review. BMC Nephrol 2025;26:115
- Virzì. Neutrophil gelatinase-associated lipocalin: biological aspects and potential diagnostic use in acute kidney injury. J Clin Med 2025;14(5):1570
- Strauß. Biomarkers of acute kidney injury: From discovery to the future of clinical practice. J Clin Anesth 2024;95:111458
- Lin. Biomarkers in pursuit of precision medicine for acute kidney injury: hard to get rid of customs. Kidney Res Clin Pract 2024;43(4):393-405
- Baeseman. Biomarker Enrichment in Sepsis-Associated Acute Kidney Injury: Finding High-Risk Patients in the Intensive Care Unit. Am J Nephrol 2023;epublished October 26th
- Jana. Proficient Novel Biomarkers Guide Early Detection of Acute Kidney Injury: A Review. Diseases 2023;11:8
- Zou. Advances in the study of subclinical AKI biomarkers. Front Physiol 2022;13:960059
Ultrasound
- Gómez-Johnson. Point-of-care ultrasound in nephrology: beyond kidney ultrasound. Diagnostics 2025;15(3):297
- Liu. Renal hemodynamic evaluation protocol based on the pathophysiological mechanism of acute kidney injury: Critical Care UltraSound Guided-A(KI)BCDE. Ren Fail 2023;45(2):2284842
- Batool. Transcending boundaries: Unleashing the potential of multi-organ point-of-care ultrasound in acute kidney injury. World J Nephrol 2023;12(4):93-103
Doppler Ultrasound
Therapy
Renal Replacement Therapy
- Liu. When to start renal replacement therapy in acute kidney injury: What are we waiting for? J Intensive Med 2024;epublished March 7th
- See. Acute kidney injury and kidney replacement therapy in adults. Singapore Medical Journal 2023;64(12):751-757
- Ostermann. Indications for and Timing of Initiation of KRT. Clin J Am Soc Nephrol 2023;18(1):113-120
- Raharjo. Dialysis Membranes for Acute Kidney Injury. Membranes 2022;12(3):325
- Villa. Hemodynamic Instability during Acute Kidney Injury and Acute Renal Replacement Therapy: Pathophysiology and Clinical Implications. Blood Purif 2021;50:729–739
- Lupuşoru. Renal replacement therapy in cancer patients with acute kidney injury. Exp Ther Med 2021;22(2):864
- Valdenebro. Renal replacement therapy in critically ill patients with acute kidney injury: 2020 nephrologist's perspective. Nefrologia 2021;epublished June 8th
- Villa. Hemodynamic Instability during Acute Kidney Injury and Acute Renal Replacement Therapy: Pathophysiology and Clinical Implications. Blood Purif 2021;epublished March 23rd
Continuous Renal Replacement Therapy
Extracorporeal Therapies
Microcirculation
Metabolism
Last updated March 31st, 2025