Critical Care Reviews Newsletter
Newsletter 473 | January 3rd 2021
Welcome to the 473rd Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's back to that time of the year where the Critical Care Reviews Meeting dominates all else on this platform.
There's just two weeks to go until eCCR21, bringing you the best critical care trials in the world. We have a number of major trial results presentations, discuss the best trials from 2020 with their chief investigators, and also feature discussions on methods and publishing. The entire 3 days is being freely live-streamed, with the full programme and url due for release later this week. Free registration will open in a few days for those wishing to obtain CPD points. For those who aren't interested in obtaining CPD points, there are no barriers to viewing the Meeting - just grab a coffee, browse to the url, watch and learn.
If you haven't yet check our our ongoing podcast series on the REMAP-CAP trial, there are 4 episodes for you to listen to, with more due imminently. It's a fascinating insight into the most advanced, complex critical care trial yet, brought to life via a collection of discussions with a range of people behind this adaptive platform trial.
I hope to have some other major developments to release very shortly too!
Randomised Controlled Articles
- Full Text: Baden. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. Ne Engl J Med 2020;epublished December 30th
- Abstract: Kirpalani. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants. N Engl J Med 2020; 383:2639-2651
- Abstract: Franklin. High flow in children with respiratory failure: A randomised controlled pilot trial - A paediatric acute respiratory intervention study. J Paediatr Child Health 2020;epublished December 30th
- Full Text: Bennett. Cerebral oximetry in adult cardiac surgery to reduce the incidence of neurological impairment and hospital length-of-stay: A prospective, randomized, controlled trial. JICS 2020;epublished December 6th
Systematic Reviews & Meta Analyses
- Full Text: Lim. Case Fatality Rates for Patients with COVID-19 Requiring Invasive Mechanical Ventilation. A Meta-analysis. Am J Respir Crit Care Med 2021;203(1):54–66
- Editorial: Angriman. Estimating the Case Fatality Risk of COVID-19 among Mechanically Ventilated Patients. Am J Respir Crit Care Med 2021;203(1):53–4
- Abstract: Sanfilippo. sSystolic dysfunction as evaluated by tissue Doppler imaging echocardiography and mortality in septic patients: A systematic review and meta-analysis. J Crit Care 2020;epublished December 31st
- Abstract: Chang. Use of recombinant activated factor VII for the treatment of perioperative bleeding in noncardiac surgery patients without hemophilia: A systematic review and meta-analysis of randomized controlled trials. J Crit Care 2020;62:164-171
- Full Text: Webb. Vasopressin in vasoplegic shock: A systematic review. World J Crit Care Med. 2020;9(5):88–98
- Full Text: Pasin. Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials. J Cardiothorac Vasc Anesth 2021;35(2):578-584
Observational Studies
- Abstract: Kassis. Reverse Trigger Phenotypes in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 2021;203(1):67–77
- Editorial: Telias. Reverse Triggering, the Rhythm Dyssynchrony: Potential Implications for Lung and Diaphragm Protection. Am J Respir Crit Care Med 2021;203(1):5–6
- Full Text: Pett. Critical care transfers and COVID-19: Managing capacity challenges through critical care networks. JICS 2020;epublished December 16th
- Full Text: Lee. Microvascular Injury in the Brains of Patients with Covid-19. N Engl J Med 2020;epublished December 30th
- Abstract: Hill. Frailty and long-term outcomes following critical illness: A population-level cohort study. J Crit Care 2021;62:94-100
- Abstract: Sutter. Serum neurofilament light chain levels in the intensive care unit: comparison between severely ill patients with and without COVID-19. Ann Neurol 2020;epublished December 30th
- Halpin. Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2021;203(1):24–36
- Sieswerda. Recommendations for antibacterial therapy in adults with COVID-19 - an evidence based guideline. Clin Microbiol Infect 2021;27(1):61-66
- Shetty. Pragmatic Recommendations for Therapeutics of Hospitalized COVID-19 Patients in Low- and Middle-Income Countries. Am J Trop Med Hyg 2020;epublished December 29th
- Informing Healthcare Decisions with Observational Research Assessing Causal Effect. An Official American Thoracic Society Research Statement. Am J Respir Crit Care Med 2021;203(1):14-23
Clinical
COVID-19
- Castells. Maintaining Safety with SARS-CoV-2 Vaccines. N Engl J Med 2020;epublished December 30th
- Kothekar. Basic Principles of Disinfection and Sterilization in Intensive Care and Anesthesia and Their Applications during COVID-19 Pandemic. Indian J Crit Care Med 2020;24(11):1114–1124
- Achaiah. R0 and Re of COVID-19: Can We Predict When the Pandemic Outbreak will be Contained? Indian J Crit Care Med 2020;24(11):1125–1127
- Martinez. Critical Obstetric Patients During the Coronavirus Disease 2019 Pandemic: Operationalizing an Obstetric Intensive Care Unit. Anesth Analg 2020;132(1):46-51
- Cassorla. Decontamination and Reuse of N95 Filtering Facepiece Respirators: Where Do We Stand? Anesth Analg 2020;132(1):2-14
- Eberli. Cardiovascular aspects of COVID-19. Swiss Med Wkly 2020;150:w20417
- Chen. Research advances in myocardial injury caused by COVID-19. Cardiovasc Diagn Ther 2020;10(4):881-887
- de Oliveira. Stroke in patients infected by the novel coronavirus and its causal mechanisms: A narrative review. JACEP Open 2020;epublished December 26th
- Jain. Management of STEMI during the COVID-19 pandemic: Lessons learned in 2020 to prepare for 2021. Trends in Cardiovascular Medicine 2020;epublished December 15th
- Ali. COVID-19 and thrombosis: From bench to bedside. Trends in Cardiovascular Medicine 2020;epublished December 16th
Neurological
Circulatory
- Mok. Macrocirculatory and Microcirculatory Endpoints in Sepsis Resuscitation. JICS 2020;epublished December 30th
- Ghosh. Chest radiography of contemporary trans-catheter cardiovascular devices: a pictorial essay. Cardiovasc Diagn Ther 2020;10(6):1874-1894
- Navaratnam. Peri-operative right ventricular dysfunction—the anesthesiologist’s view. Cardiovasc Diagn Ther 2020;10(5):1725-1734
- Klinke. Emerging therapies for right ventricular dysfunction and failure. Cardiovasc Diagn Ther 2020;10(5):1735-1767
Respiratory
Hepatobiliary
- Kharasch. Peer Review Matters: Research Quality and the Public Trust. Anesthesiology 2021;134:1–6
- See. How I prescribe continuous renal replacement therapy. Crit Care 2021;25:1
- Vincent. The fluid challenge. Crit Care 2020;24:703
- Maslove. Artificial intelligence in telemetry: what clinicians should know. Intensive Care Med 2021;epublished January 2nd
- Bauchner. A Medical and Scientific New Year’s Wish List. JAMA 2020;epublished December 23rd
- Pisano. Indications for Tracheal Intubation in Patients With Coronavirus Disease 2019 (COVID-19). J Cardiothorac Vasc Anesth 2020;epublished December 2nd
- So. Chasing the Cardiogenic Shock Unicorn. J Cardiothorac Vasc Anesth 2021;35(2):366-367
- Seelhammer. Survivorship After Sudden Cardiac Arrest: Establishing a Framework for Understanding and Care Optimization. J Cardiothorac Vasc Anesth 2021;35(2):368-373
- Ortoleva. Anesthetic Considerations for Recovered COVID-19 Patients. J Cardiothorac Vasc Anesth 2021;35(2):376-377
- Abbasi. COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation. JAMA 2020;epublished December 30th
- Balhara. “The Guts to Really Look at It”—Medicine and Race in Robert Colescott’s Emergency Room. JAMA 2020;epublished December 21st
- Hu. Who Is the Parasite?—COVID-19 and Structural Narratives of Health Inequity. JAMA 2020;epublished December 21st
- Methangkool. Progress in Patient Safety in Anesthesia. JAMA 2020;324(24):2485-2486
- Baric. Emergence of a Highly Fit SARS-CoV-2 Variant. N Engl J Med 2020; 383:2684-2686
- Schober. Linear Regression in Medical Research. Anesth Analg 2021;132(1):108-109
- Perakslis. Digital Health—The Need to Assess Benefits, Risks, and Value. JAMA 2020;epublished December 28th
- Easter. Outcomes of Critically Ill Pregnant Women with COVID-19 in the United States. Am J Respir Crit Care Med 2021;203(1):122–125
- Schinkel. What Sepsis Researchers Can Learn from COVID-19. Am J Respir Crit Care Med 2021;203(1):125–127
- Gao. Comparing Nasopharyngeal and BAL SARS-CoV-2 Assays in Respiratory Failure. Am J Respir Crit Care Med 2021;203(1):127–129
- Blot. Is IL-6 the Right Target in COVID-19 Severe Pneumonia? Am J Respir Crit Care Med 2021;203(1):139–140
- Inoue. Role of IL-6 in Severe Inflammation. Am J Respir Crit Care Med 2021;203(1):140–141
- McElvaney. Reply to Blot et al. and to Inoue et al. Am J Respir Crit Care Med 2021;203(1):141–142
- Tobin. Respiratory Drive Measurements Do Not Signify Conjectural Patient Self-inflicted Lung Injury. Am J Respir Crit Care Med 2021;203(1):142–143
- Various. Neutralizing Antibody LY-CoV555 for Outpatient Covid-19. N Engl J Med 2020;epublished December 30th
- Various. Tocilizumab in Covid-19. N Engl J Med 2020;epublished December 22nd
- Various. Visualization of SARS-CoV-2 in the Lung. N Engl J Med 2020; 383:2689-2690
- Morais. Bedside Electrical Impedance Tomography Unveils Respiratory “Chimera” in COVID-19. Am J Respir Crit Care Med 2021;203(1):120–121
- Mayet. COVID-19-associated acute kidney injury: after the tubule and the glomerulus, now the vessel? Clin Kid J 2020;13(6):1105–1106
- Prakash. Challenges Faced in Managing an Adult Uncorrected Tetralogy of Fallot Patient with Pneumonia and Septic Shock in the Intensive Care Unit. Indian J Crit Care Med 2020;24(11):1135–1136
- Gold. A Rare and Unique Central Line Complication. J Cardiothorac Vasc Anesth 2021;35(2):676-677
Until next week
Rob