Critical Care Reviews Newsletter
Newsletter 476 | February 1st 2021
Prof Bodil Steen Rasmussen presents the HOT-ICU trial results at eCCR21
Welcome to the 476th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature for the week of January 18th to 24th. This was the week of the Critical Care Reviews Meeting, which partly explains why I'm behind with this and why it's such a small issue. Last week's newsletter should be out tomorrow. Newsletter 475 wasn't emailed as I was having issues with the website, from where it's now available.
The highlight of this edition is the HOT-ICU randomised controlled trial, which was presented at eCCR21 and simultaneously published by the New England Journal of Medicine. The recording of the presentation is presently available in an unedited version on the meeting webpage - day 1 video, starting at 2 hours, 44 minutes, 20 seconds. I'll hopefully get the edited version up this week.
New Look Website
The CCR website has been updated, with a new look and more streamlined interface. The old site contained over 9000 webpages, diluting attention on the major evidence in our specialty. The new site refocuses on critical care trials, with the homepage highlighting the latest major trials, studies and guidelines. It will take a while to repopulate the site, but I'll hopefully have the importation complete by the end of February. The additional pages will be added daily as they are completed. There are sections on major trials, major guidelines and hot articles to add, as well as the archive of all 473 previous newsletters.
eCCR Attendance Certificate
If you watched eCCR21, or get the newsletter regularly, or use the CCR website, podcast or books, then please consider supporting the project. Over the past 11 years it has grown enormously, to the point where it far exceeds my ability to run it in my spare time. Everything within the CCR project is made freely available for the benefit of all. If you find the CCR project a valuable service, both personally and for the wider critical care community, and are in a position to be able to make a small contribution, then please consider supporting it.
Support CCR
For those of you who registered for eCCR21 and are having difficultly accessing the attendance certificate, please reply to this email. My apologies for the trouble, but, as mentioned, I've had issues with the website over the past few weeks, which I've now mostly resolved. The unedited recording of the entire 3 days of the meeting is available to watch on the meeting webpage. This includes 5 major trial results, 14 of the best trials of 2020 presented by their chief investigators and accompanied by independent editorials, plus talks on pandemic publishing, pilot trials and the John Hinds Lecture.
Randomised Controlled Trials
Systematic Reviews & Meta Analyses
- Mitra. Concurrent Use of Renal Replacement Therapy during Extracorporeal Membrane Oxygenation Support: A Systematic Review and Meta-Analysis. J Clin Med 2021;10(2):241
- Song. Low- versus High-Chloride Content Intravenous Solutions for Perioperative Patients: A Systematic Review and Meta-Analysis. Biomed Res Int 2021;2021:3571397
Observational Studies
Clinical
- Page. Mechanisms of thrombosis and cardiovascular complications in COVID-19. Thromb Res 2021;200:1-8
- Barchitta. Lung Semiotics Ultrasound in COVID-19 Infection. J Cardiovasc Echogr 2020;30(Suppl 2):S1–S5
- Cianci. Lung Ultrasound in the COVID-19 Pandemic. J Cardiovasc Echogr 2020;30(Suppl 2):S6–S10
- Cresti. Echocardiography and Multimodality Cardiac Imaging in COVID-19 Patients. J Cardiovasc Echogr 2020;30(Suppl 2):S18–S24
- Landini. The Role of Imaging in COVID-19 Pneumonia Diagnosis and Management: Main Positions of the Experts, Key Imaging Features and Open Answers. J Cardiovasc Echogr 2020;30(Suppl 2):S25–S30
- Greatorex. Echocardiographic assessment and critical care management of peri-partum women with unexpected left ventricular failure. JICS 2021;epublished January 5th
- Passi. The patient with cirrhosis in the intensive care unit and the management of acute-on-chronic liver failure. JICS 2020;epublished December 28th
- Asim. A contemporary insight of metabolomics approach for COVID-19: Potential for novel therapeutic and diagnostic targets. Nepal J Epidemiol 2020;10(4):923-927
- Amodio. Lights and Shadows in Hepatic Encephalopathy Diagnosis. J Clin Med 2021;10(2):341
- Łagocka. Favipiravir in Therapy of Viral Infections. J Clin Med 2021;10(2):273
- Iba. Proposal of the Definition for COVID-19-Associated Coagulopathy. J Clin Med 2021;10(2):191
- Wennig. Mushroom Poisoning. Dtsch Arztebl Int 2020;117:701-8
- Jung. Frailty as a Prognostic Indicator in Intensive Care. Dtsch Arztebl Int 2020;117:668-73
Pre-Clinical
- Tukpah. COVID-19 Racial and Ethnic Inequities in Acute Care and Critical Illness Survivorship. Ann Am Thor Soc 2021;18(1):23-25
- Lazzeri. Echocardiographic assessment of the right ventricle in COVID -related acute respiratory syndrome. Intern Emerg Med 2021;16:1–5
- Izzedine. Acute kidney injury in patients with COVID-19: an update on the pathophysiology. Nephrol Dial Transplant. 2021;36(2):224–226
- Ho. Is Tranexamic Acid for Upper Gastrointestinal Bleeding Under Debate? Ann Emerg Med 2021;77(2):279-281
- David. Adjuvant therapeutic plasma exchange in septic shock. Intensive Care Med 2021;epublished January 20th
- Herman. COVID-19: Airway management considerations. Anaesthesiol Intensive Ther 2020;52(4):339–340
- Gómez-Ríos. The role of videolaryngoscopy in airway management of COVID-19 patients. Anaesthesiol Intensive Ther 2020;52(4):344–345
- Yamamoto. Risk of propofol use for sedation in COVID-19 patient. Anaesthesiol Intensive Ther 2020;52(4):354–355
- Pilcher. Learning from the First Wave of the Pandemic in England, Wales and Northern Ireland. Am J Respir Crit Care Med 2021;epublished January 21st
- Gonçalves. An unwanted intruder. Neth Heart J 2021;29:111–112
- Nguyên. Slowing down too fast. Neth Heart J 2021;29:113–114
- Martelli. Pneumothorax and pulmonary air leaks as ventilator-induced injuries in COVID-19. Acute Crit Care 2021;epublished January 13th
- Bylund. Man With Shortness of Breath. Ann Emerg Med 2021;77(2):178
- Fiutko. Man With Double Vision. Ann Emerg Med 2021;77(2):220
- Manzur-Sandoval. Giant inverted T waves in a patient with COVID-19 infection. Ann Emerg Med 2021;77(2):264-267
- Tu. Woman With Fever and Drowsiness. Ann Emerg Med 2021;77(2):e71-e72
- Lambermont. SARS-CoV-2 in carotid body. Intensive Care Med 2021;epublished January 22nd
Until next week
Rob