Critical Care Reviews Newsletter
Newsletter 489 | April 25th 2021
Welcome to the 489th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days.
The highlights of this week's edition are randomised controlled trials on suvratoxumab for the prevention of Staphylococcus aureus ventilator-associated pneumonia & aspirin versus anticoagulation in cervical artery dissection; systematic reviews and meta analyses on refeeding syndrome & corticosteroids in COVID-19 and non-COVID-19 ARDS; and observational studies on the impact of frailty on survival in elderly intensive care patients with COVID-19 & death in hospital following ICU discharge: insights from the LUNG SAFE study.
There are also narrative reviews on embolization in trauma & long-term outcomes and the post-intensive care syndrome in critically ill children; an editorial on ventilator-associated pneumonia in the era of COVID-19 pandemic; and commentaries on gender imbalance in intensive care & remote research and clinical trial integrity during and after the Coronavirus pandemic; as well as correspondence on emergency intubation in Covid-19 & cytokine storm.
If you only have time to read one article this week, try this one on nasal potential difference in patients with, and at risk of, acute respiratory distress syndrome. Ok, I'm slightly biased....
Research
Randomised Controlled Trials
- François. Efficacy and safety of suvratoxumab for prevention of Staphylococcus aureus ventilator-associated pneumonia (SAATELLITE): a multicentre, randomised, double-blind, placebo-controlled, parallel-group, phase 2 pilot trial. Lancet Infect Dis 2021;epublished April 21st
- Engelter. Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial. Lancet Neurology 2021;20(5):341-350
- Zhao. Effects of erector spinae plane block and retrolaminar block on analgesia for multiple rib fractures: a randomized, double-blinded clinical trial. Braz J Anesth 2021;epublished April 22nd
- Georgevici. Negative drift of sedation depth in critically ill patients receiving constant minimum alveolar concentration of isoflurane, sevoflurane, or desflurane: a randomized controlled trial. Crit Care 2021;25:141
- Darazam. Role of interferon therapy in severe COVID-19: the COVIFERON randomized controlled trial. Sci Rep 2021 Apr 13;11(1):8059
- El-Nawawy. Outcome of Early Hemostatic Intervention in Children With Sepsis and Nonovert Disseminated Intravascular Coagulation Admitted to PICU: A Randomized Controlled Trial. Pediatr Crit Care Med 2021;22(3):e168-e177
Systematic Reviews & Meta Analyses
- Cioffi. The incidence of the Refeeding Syndrome. A systematic review and meta-analyses of literature. Clin Nutrition 2021;epublished April 21st
- Owen. Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: a systematic review and meta-analysis. Crit Care 2021;25:146
- Chaudhuri. Corticosteroids in COVID-19 and non-COVID-19 ARDS: a systematic review and meta-analysis. Intensive Care Med 2021;epublished April 19th
- Yang. High-flow nasal cannula for acute exacerbation of chronic obstructive pulmonary disease: A systematic review and meta-analysis. Heart Lung 2021;50(2):252-261
- Dmytriw. Outcomes of acute respiratory distress syndrome in COVID-19 patients compared to the general population: A systematic review and meta-analysis. Expert Rev Respir Med 2021;epublished April 21st
- Wang. The use of non-invasive ventilation in COVID-19: A systematic review. J Infect Dis 2021;106:254-261
Observational Studies
- Mac Sweeney. Transepithelial nasal potential difference in patients with, and at risk of acute respiratory distress syndrome. Thorax 2021;epublished April 22nd
- Jung. The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study. Crit Care 2021;25:149
- Madotto. Death in hospital following ICU discharge: insights from the LUNG SAFE study. Crit Care 2021;25:144
- Dauger. Necrotizing soft-tissue infections in pediatric intensive care: a prospective multicenter case-series study. Crit Care 2021;25:139
- Lebreton. Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort study. Lancet Respir Med 2021;epublished April 19th
- Fung. Electrographic Seizures and Outcome in Critically Ill Children. Neurology 2021;epublished April 23rd
Guidelines
- Expert consensus on perioperative management of liver transplantation in adults with acute-on-chronic liver failure. Liver Research 2021;epublished April 20th
- Donato. Consensus for the management of analgesia, sedation and delirium in adults with COVID-19-associated acute respiratory distress syndrome. Rev Bras Ter Intensiva 2021;33(1):48-67
Reviews
Clinical
COVID-19
- Dreucean. Approach to Sedation and Analgesia in COVID-19 Patients on Venovenous Extracorporeal Membrane Oxygenation. Ann Pharmacother 2021;epublished April 22nd
- Singh. High-Flow Nasal Cannula, a Boon or a Bane for COVID-19 Patients? An Evidence-Based Review. Current Anesthesiology Reports 2021;epublished March 2nd
- Garg. Neuroimaging Patterns in Patients with COVID-19-Associated Neurological Complications: A Review. Neurol India 2021;69:260-71
Neurological
- Nogueira. Cerebral Autoregulation in Ischemic Stroke: From Pathophysiology to Clinical Concepts. Brain Sci 2021;11(4):511
- Kennouche. Bedside voluntary and evoked forces evaluation in intensive care unit patients: a narrative review. Crit Care 2021;25:157
Airway
Respiratory
- Dwivedi. Pulmonary Hypertension in Association with Lung Disease: Quantitative CT and Artificial Intelligence to the Rescue? State-of-the-Art Review. Diagnostics 2021;11(4):679
- Rousseau. Endovascular therapies for pulmonary embolism. Heliyon 2021;7(4):e06574
- MacLeod. Chronic obstructive pulmonary disease exacerbation fundamentals: Diagnosis, treatment, prevention and disease impact. Respirology 2021;epublished April 24th
Gastrointestinal
Hepatobiliary
Renal
Haematological
Sepsis
- Darden. Dysregulated Immunity and Immunotherapy after Sepsis. J Clin Med 2021;10(8):1742
- Barker. Lipid and Lipoprotein Dysregulation in Sepsis: Clinical and Mechanistic Insights into Chronic Critical Illness. J Clin Med 2021;10(8):1693
- Lade. Bacterial Targets of Antibiotics in Methicillin-Resistant Staphylococcus aureus. Antibiotics 2021;10(4):398
- Kakoullis. Mechanisms of Antibiotic Resistance in Important Gram-Positive and Gram-Negative Pathogens and Novel Antibiotic Solutions. Antibiotics 2021;10(4):415
- Gavelli. Management of sepsis and septic shock in the emergency department. Intern Emerg Med 2021;epublished April 22nd
Trauma
- Pillai. Where Does Interventional Radiology Fit in with Trauma Management Algorithm? Semin intervent Radiol 2021;38(01):003-008
- Lopera. Embolization in Trauma: Review of Basic Principles and Techniques. Semin intervent Radiol 2021;38(01):018-033
- Savioli. Trauma-Induced Coagulopathy: Overview of an Emerging Medical Problem from Pathophysiology to Outcomes. Medicines 2021;8(4):16
Paediatrics
- Bhaskar. Use of ECMO for Cardiogenic Shock in Pediatric Population. J Clin Med 2021:10(8):1573
- Woodruff. Long-Term Outcomes and the Post-Intensive Care Syndrome in Critically Ill Children: A North American Perspective. Children 2021;8(4):254
Miscellaneous
Non-Clinical
Pre-Clinical
Commentaries
- Vincent. Addressing gender imbalance in intensive care. Crit Care 2021;25:147
- Hess. Loss of a Legend: Remembering Robert M. Kacmarek. Respir Care 2021;epublished April 21st
- Upadhye. VICE raises the GRADE: recommendations for CAEP clinical practice guidelines. Can J Emerg Med 2021;epublished April 20th
- McDermott. Remote Research and Clinical Trial Integrity During and After the Coronavirus Pandemic. JAMA 2021;epublished April 22nd
- Zider. Start With All the Little Things. JAMA 2021;325(15):1509-1510
Correspondence
- Eisenga. Iron Deficiency Defined by Hepcidin in Critically Ill Patients. Crit Care 2021;25:138
- Abraham. Trauma patients do not benefit from a viscoelastic haemostatic assay-guided protocol, but why? Intensive Care Med 2021;epublished April 15th
- Various. Cytokine Storm. N Engl J Med 2021;384:e59
- Various. Emergency Intubation in Covid-19. N Engl J Med 2021;epublished April 21st