Critical Care Reviews Newsletter

Welcome to the 545th Critical Care Reviews Newsletter, bringing you the best critical care research and open access articles from across the medical literature over the past seven days. It's a massive edition this week, with a host of fantastic articles throughout all sections.

However, our focus at present is on CCR22, which is now just 3 weeks away. I'm delighted to add the SuDDICU trial results presentation to the programme. This has been a Herculean effort, with a planned 15,000 patients to be enrolled in this multicentre, crossover, cluster randomised controlled trial investigating selective digestive decontamination. This strategy to clear the digestive tract of potentially pathological organisms includes frequent application of an oral antibiotic paste, gastric antibiotic suspension and an intravenous antibiotic. The primary outcome is hospital mortality, up to day 90. Profs John Myburgh and Ian Seppelt (Sydney) will present the results, with Prof John Marshall (Toronto) delivering the editorial.

If you plan on attending CCR22, there is still some space, but the late rush is now happening so don't delay. The Friday night social event is sold out, and the Wednesday and Thursday night social events are filling up and look like selling out also. We've had a cancellation in the creche, so there is a place available. If you aren't able to make it in person, the entire meeting is being freely livestreamed on the Critical Care Reviews website. If you watch virtually and wish to avail of the 18 CPD/CME points, accredited by the Royal College of Anaesthetists, then please register on the website for a relatively low cost. With 6 major trial result presentations, reviews of 8 of the best trials of the past year with their chief investigators, three panel discussions and the annual honorary John Hinds Lecture, the Critical Care Care Reviews Meeting, June 15th to 17th at Titanic Belfast, will be the place to be. Don't miss it!

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