EVIDENCE Trial Results Presentation
Mark Dennis (Melbourne) and Brian Burns (Sydney) present the results of the EVIDENCE trial at Critical Care Reviews Down Under 2024 at The Edge, Melbourne. An independent editorial is delivered by Stephen Bernard (Melbourne). The panelists are Marion Campbell (Aberdeen), Kiran Shekar (Brisbane), Bridget Dicker (Auckland), and Jacob Steinmetz (Copenhagen). The session is chaired by Chris Nickson (Melbourne). The EVIDENCE trial investigated expediated out-of-hospital cardiac arrest care, including in-hospital ECMO and advanced CPR methods.
Lancet Respiratory Medicine Paper
Interview with the Trialists
Journal Watch Latest
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Randomised Controlled Trial

Guideline

Narrative Reviews
Frat. Noninvasive respiratory supports in ICU. Intensive Care Med 2025;51:1476–1489
added August 21st

Narrative Review
added August 21st

Guideline
added August 20th

Randomised Controlled Trial
added August 20th

Editorial

Narrative Review
Cashmore. Transcranial ultrasound in the critically ill patient: a narrative review. ICMx 2025;13:86
added August 19th

Guideline

Systematic Review & Meta Analysis

Narrative Review

Commentary

Narrative Review
Yamamoto. Mechanism of sepsis. J Mol Pathol 2025;6:18
added August 14th

Narrative Review

Randomised Controlled Trial
TIGRIS Trial Result Press Release - Polymyxin B Hemoadsorption Therapy for Endotoxic Septic Shock
- Results exceed prespecified primary endpoint of 95% posterior probability of benefit for PMX on 28-day mortality
added August 13th

Randomised Controlled Trial
added August 13th
CCR Meeting Talks
After 14 meetings, we have a huge collection of superb presentations. We'll showcase them here, one at a time.
CCR19
APROCCHSS Trial Review
Prof Djillali Annane (Paris) discusses the APROCCHSS trial, investigating fludrocortisone and hydrocortisone in septic shock.
added August 17th
CCR Down Under 2025 Trials to Date
Join us in Melbourne, December 9th & 10th, to discuss the best critical care trials in the world
CCR Content

Paper of the Day
Saturday, August 23rd
Join us to read one paper per day and cover the spectrum of critical care across 2025. Previous papers of the day are available here.

Highlighted Narrative Reviews
With thousands of open access narrative reviews listed across the website, CCR provides a comprehensive educational resource. We'll highlight one topic here every few days. Today, we look at Acute Kidney Injury
added August 20th

Foundational Trials
It's the latest in our Foundational Trials collection, looking at the trials which underpin contemporary critical care practice
added August 19th

Newsletter 714
Critical Care Reviews Newsletter 714, bringing you the best critical care research and open access articles for the week August 11th to 17th.
Subscriptions are available to individuals and departments.
added August 18th

Highlighted Guidelines
Need a guideline, or just want to refresh your knowledge on the evidence-based management of a particular condition? We provide more up-to-date guidelines than any other critical care resource. Have a look at our ARDS Guideline section
added August 12th
CCR Down Under 2025

Registration has opened for CCR Down Under in Melbourne, on December 9th and 10th, again at the Edge in Federation Square.
We aim to bring another set of fantastic international critical care trials to Australia. If you are interested in the science underlying clinical practice, this is the meeting for you.
We're delighted to be partnering once again with the Alfred Intensive Care Academic Centre, and this year, with Monash University.
If you missed the presentations last December, the presentations of the so far published trials are available here.


