Critical Care Reviews Meeting 2025
The best critical care trials in the world
June 11th to 13th, 2025 | Titanic Belfast
Trial Results Presenters
First presentations of major trials results

Valentina Ajello
Dr. Valentina Ajello is an Italian anesthesiologist, specialising in cardio-thoracic anesthesia and intensive care. She currently serves as the Acting Head of the Cardio-Thoracic Anesthesia Unit at Policlinico Tor Vergata in Rome, a role she assumed in June 2023, following her extensive tenure as a senior specialist with managerial responsibilities within the same unit. Since beginning her career in anesthesiology in 2004, Dr. Ajello has developed expertise in perioperative critical care for cardiac surgeries, advanced hemodynamic monitoring, transesophageal echocardiography (TEE), and the management of complex cardiovascular conditions such as cardiogenic shock and severe heart failure with mechanical circulatory support, like VA-ECMO and Impella.
Beyond her clinical work, Dr. Ajello is involved in academic and educational activities. She has been a Clinical Tutor at the University of Rome “Tor Vergata” since 2012 and recently became a lecturer in Anesthesiology for undergraduate and master’s programs, focusing on topics such as transfusion medicine and anticoagulation. A certified expert in adult TEE by the European Society of Cardiology, she is an active member of multiple scientific societies including EACTAIC, where she contributes to the Echo Subcommittee and the ESC/EACTAIC joint TEE certification exams.

Karen Bosma
Dr. Karen J. Bosma received her Bachelor of Arts & Science and MD degrees from McMaster University, Hamilton, Canada. She completed a residency in Internal Medicine and a combined Respirology & Critical Care Fellowship at The University of Western Ontario, followed by a research fellowship in Torino, Italy. While in Italy, her research was focused on the relationship between patient-ventilator interaction and sleep quality and the impact of ventilation practices on lung function in potential organ donors and brain-injured patients.
Dr. Bosma is currently an Associate Professor of Medicine at the Schulich School of Medicine & Dentistry, Associate Scientist at the Lawson Health Research Institute, and Attending Consultant, Medical-Surgical Intensive Care Unit, University Hospital in London, Canada. Her current research interests include patient-ventilator interaction and its impact on sleep, delirium and weaning from mechanical ventilation, and proportional-assist ventilation.

Laurent Brochard
Dr. Laurent Brochard is the Interdepartmental Division Director, Critical Care, at the University of Toronto. He is a full professor and clinician-scientist in the Division of Critical Care at St. Michael’s Hospital. He was previously working in Geneva as head of the Intensive Care Unit of the Geneva University Hospital, in Switzerland for three years. Most of his career took place at Henri Mondor Hospital, Assistance Publique – Hôpitaux de Paris, and at Paris EST University, France.
Laurent has a strong involvement in research, and especially clinical research about mechanical ventilation. He has been editor-in-chief of the journal, Intensive Care Medicine, from 2001 to 2007 and is currently serving as deputy editor for the American Journal of Respiratory and Critical Care Medicine. He is leading a European Research Network dedicated to clinical studies in mechanical ventilation called REVA.

Lauralyn McIntyre
Dr. Lauralyn McIntyre is an Intensivist and Critical Care Research Chair at the Ottawa Hospital, an Associate Professor in the Department of Medicine with a Cross Appointment to the Department of Epidemiology and Community Medicine at the University of Ottawa, and a Senior Scientist with the Ottawa Hospital Research Institute. She has served on the executive of the Canadian Critical Care Trials Group (CCCTG), is a member of the Translational Biology Group (CCCTBG), Co-Chair of the grants and manuscripts committee for Sepsis Canada and was a panel member (2106) and panel Co-Chair (2021) for the Surviving Sepsis Guidelines.
Lauralyn has published 225 peer-review articles and has mentored many undergraduate students and postgraduate trainees throughout her career. Her peer-reviewed funded research programs span from highly experimental and translational to usual care research questions that are multi-method and multi-disciplinary and focus on randomized trials related to fluid resuscitation and transfusion of stem cells in the acutely ill and septic shock. Throughout her career, Dr. McIntyre has collaborated locally and nationally with CCCTG and CCCTBG researchers across 33 adult and pediatric research programs.

Monica Taljaard
Monica Taljaard is a Senior Scientist in the Methodological and Implementation Research Program at the Ottawa Hospital Research Institute (OHRI) and Full Professor in the School of Epidemiology and Public Health at the University of Ottawa. Her main research interests are in the design, analysis and ethics of pragmatic and cluster randomized trials. As a methodologist with the Ottawa Methods Centre, she works with clinicians and researchers from a variety of backgrounds in the design and analysis of their studies including clinical trials and observational studies. She has published over 500 peer reviewed journal articles and helped secure >$190 million in peer-reviewed research grants, including >$60M as principal or co-principal investigator. She is Deputy Editor of Clinical Trials: Journal of the Society for Clinical Trials.

Fabrizio Monaco
Dr. Fabrizio Monaco, MD is currently Head of Cardio-Thoracic and Vascular Anesthesia at IRCCS San Raffaele Scientific Institute and Assistant Professor (Clinical) in Anesthesiology. His main research and academic interests are perioperative medicine, cardio-thoracic anesthesia and intensive care, mechanical circulatory support and anesthetic pharmacology. He also serves as Co-Chair of the EACTAIC Sub-Committee on Cardiopulmonary Bypass, ECMO and Mechanical Circulatory Support.
Twitter: @md_monaco

Ewan Goligher
Ewan Goligher MD, PhD is Associate Professor of Medicine and Physiology in the Interdepartmental Division of Critical Care Medicine at the University of Toronto and a Senior Scientist at the Toronto General Hospital Research Institute.
His clinical and translational research program focuses on the mechanisms and impact of lung and diaphragm injury during mechanical ventilation and extracorporeal life support. He serves as co-chair of the PRACTICAL international adaptive platform trial testing a range of novel interventions for acute hypoxemic respiratory failure.

Martin Dres
Dr. Martin Dres is Assistant Professor of Medical Critical Care at APHP, Sorbonne University in Paris, France. He has a background in respiratory physiology, with a particular focus on lung and heart interactions and mechanical ventilation.
Dr. Martin Dres has developed a research program dedicated to diaphragm dysfunction and respiratory muscles explorations in the intensive care unit. He contributed to the development of diaphragm ultrasound and diaphragm function assessment in critically ill patients. He has authored and co-authored >100 publications related to mechanical ventilation, weaning failure, and assessment of respiratory muscles in patients under mechanical ventilation.

Michaël Chassé
Michaël Chassé is a medical specialist in intensive care at the Centre hospitalier de l'Université de Montréal (CHUM), a principal scientist at the CHUM Research Centre and an associate professor in the Department of Medicine and the School of Public Health at the Université de Montréal. He also holds a PhD in Epidemiology from the University of Ottawa. He is Associate Scientific Director of Data Science at the CHUM Research Centre and the Scientific Director of the CHUM Centre for The Integration and Analysis of Medical Data (CITADEL) which brings together a scientists and professionals specialized in health data science, biostatistics, bioinformatics and machine learning.
His main research interests focus on improving traditional methods of epidemiological research using new technologies such as machine learning and innovative clinical trials, particularly in areas related to intensive care such as organ donation and death determination, organ transplantation and blood transfusions.
Twitter: @Michael_Chasse

Jai Shankar
Dr Jai Shankar is a diagnostic and interventional Neuroradiologist in Winnipeg, Canada. He is Professor and Associate Head of Research and Academics, Department of Radiology, University of Manitoba, Winnipeg, Canada. His research focuses on perfusion imaging in stroke and critically ill patients as well as in several interventional neuroradiology fields.
He leads several cohort studies on the role of CT perfusion in patients in ICU, severe traumatic brain injury and comatose cardiac arrest patients. He leads the randomized control trial on Embolization of middle meningeal artery (EMMA) for Subdural Hematoma (EMMA Can)

Stephanie Parks Taylor
Dr. Taylor is the J. Griswold and Margery Hopkins Ruth Research Professor of Medicine and the Chief of Hospital Medicine at the University of Michigan. Her research focuses on using rigorous methods to develop and test complex health interventions to improve outcomes for hospitalized patients.
She leads multiple pragmatic trials and is known for her work on both early treatment of sepsis and optimizing recovery practices for sepsis survivors.
Twitter: @StephptaylorCLT

Marion Moseby-Knappe
Dr. Marion Moseby-Knappe is a Consultant Neurologist at the Department of Neurorehabilitation at Skåne University Hospital in Lund, Sweden. She holds a PhD within neurological prognostication after cardiac arrest from Lund University. Her main research interest is understanding brain injury and optimizing the prediction of outcome after cardiac arrest. Together with the team at Lund University Centre for Cardiac Arrest, she has published prognostic studies on brain injury biomarkers, neuroimaging, neurophysiology and neurological prognostication within the TTM1 and TTM2 trials.
Marion is responsible for the neurological prognostication within the international multicentre STEPCARE trial, and principal investigator of the EARLY-NEURO substudy combining biomarkers, computed tomography and electroencephalography for early neuroprognostication.

Niklas Nielsen
Niklas Nielsen is professor of anesthesiology and intensive care at Lund University, Sweden and vice dean of the Medical Faculty. He has during the last two decades been leading large international cardiac arrest studies and trials building a network of over 80 hospitals in 18 countries focusing on targeted temperature management for ischemic brain damage and prognostication of outcome.
The trials, TTM1 and TTM2, have had considerable impact on clinical guidelines worldwide for post cardiac arrest care, neuroprognostication and follow-up. He is now chief investigator for the STEPCARE project, a randomizied trial with 3500 participants looking into fever management, sedation strategies and level of mean arterial pressure after cardiac arrest.
He would love to sail to the Critical Care Reviews Belfast meeting.

Andrew Klein
Andrew Klein is a Consultant at Royal Papworth Hospital Deparment of Anaesthesia and Intensive Care. He is the former Editor-in-Chief of the journal Anaesthesia and the Vice-President of the Association of Anaesthetist.
Andrew’s main research interests are improving outcomes after major surgery and iron/B12 deficiency and anaemia. Andrew is a keen cricket supporter and lifelong and long-suffering West Ham fan.

Siddesh Shetty
Dr. Siddesh Shetty is a health economics researcher at the Faculty of Life Sciences & Medicine, King’s College London. He specialises in decision modelling, value-of-information analysis, and economic evaluation alongside clinical trials. He is actively contributing to NIHR-funded studies in cardiovascular surgery, multi morbidity and maternal and child health.
Previously, he worked as a medical scientist for the Ministry of Health and Family Welfare in India, where he conducted economic evaluations to inform public health policies. His research has influenced WHO's recommendations for managing postpartum haemorrhage.

Paul Mouncey
Paul is Co-Director, and Clinical Trials Unit Director, at the Intensive Care National Audit & Research Centre (ICNARC) . Paul is an epidemiologist with over 20 years’ experience of conducting multicentre randomised clinical trials, initially in Cancer, but at ICNARC focussed in adult and paediatric critical care. Paul is the Joint-Chief Investigator for the UK-ROX trial - a highly challenging trial within the critical care setting, using extensive data collected routinely by the national clinical audit for critical care (Case Mix Programme) database.
Paul led the development of the NIHR-funded PIVOTAL adaptive platform trial evaluating multiple interventions in paediatric critical care and sits on the REMAP-CAP International Trial Steering Committee. He sits on both the NIHR Critical Care National Specialty Group, which has responsibility for overseeing delivery of studies on the NIHR portfolio for critical care, and the UK Critical Care Research Group.
Twitter: @PaulMouncey

Daniel Martin
Daniel is Professor of Perioperative and Intensive Care Medicine at the University of Plymouth and a consultant in intensive care medicine at Derriford Hospital in Plymouth. He has a PhD in applied physiology from University College London and his main research interest is focused on the physiology and clinical implications of too much or too little oxygen. He has been involved in several research expeditions to high altitude and in 2007 summited Mount Everest with the Xtreme Everest team; an blood gas taken from him near the summit showed one of the lowest arterial oxygenation readings ever recorded in a human. Daniel is a chief investigator for the UK-ROX trial evaluating conservative oxygen therapy in mechanically ventilated patients and the EXAKT sub-study to assess the accuracy of pulse oximeters in patients with different skin tones. He is the editor in chief of the Journal of the Intensive Care Society and in 2016 was awarded Officer of the Order of the British Empire (OBE), for services to the prevention of infectious diseases.

Kathryn Maitland
Kathryn Maitland is Professor of Paediatrics at Imperial College, London and is based full-time in East Africa, where she leads a research group whose portfolio includes severe malaria, bacterial sepsis and severe malnutrition in children. Her team conducted the largest trial in critically children ever undertaken in Africa (FEAST trial) examining fluid resuscitation strategies in children with severe febrile illness, showing that fluid boluses increased mortality. She has also lead the landmark TRACT trial, investigating transfusion and other treatment strategies in 3800 African children severe life-threatening anaemia, and the COAST trial (Children Oxygenation Administration Strategies Trial) examining the optimum oxygen saturation threshold for which oxygen should be targeted and how best to administer oxygen, by high flow or low flow, in 4200 severely ill African children. In recognition of her contribution to medical research and healthcare she was recently elected to Fellowship of the Academy of Medical Sciences.
Twitter: @KathMaitland

Elizabeth George
Dr. Elizabeth George is a statistician and researcher with 15 years of experience working on clinical trials focused on acutely ill children presenting to hospitals in Africa. She has contributed to award-winning large trials that have challenged the status quo, led to changes in guidelines, and provided crucial evidence supporting existing guidelines. These trials have sparked numerous global debates and discussions. Her work has included trials on fluid resuscitation for pediatric shock, blood transfusion volumes for severe anemia, antibiotics for severe malaria and bacterial co-infection, and fluids for children with gastroenteritis with or without severe malnutrition.
Dr. George leads subsequent analyses, publications, and dissemination projects from these trials, developing analysis plans and collaborating closely with colleagues. She has also served as a trial statistician for smaller trials that have clarified underlying mechanisms and helped inform future research.
Dr. George is passionate about conducting high-quality clinical trials to answer critical questions and provide evidence for treatment guidelines for children presenting to hospitals in Africa.
Twitter: @lcgeorge13

Lee-anne Chapple
Lee-anne Chapple is the Senior Critical Care Dietitian at the Royal Adelaide Hospital, and Associate Professor at the University of Adelaide in Australia. She leads the intensive care nutrition research program at the Royal Adelaide Hospital, focusing on protein delivery and utilisation, post-ICU nutrition, and recovery.
A/Prof Chapple has collaborated on more than 90 research publications and received more than $10 million Australian dollars in research funding. She was the post-doctoral research fellow and co-Project Manager for the TARGET Protein trial.
Twitter: @LSChapple

Matthew Summers
Matt is a Research Dietitian at the Royal Adelaide Hospital and PhD candidate at University of Adelaide. Matt has worked within the Intensive Care Unit Research Department at the Royal Adelaide Hospital for over 15 year and most recently co-project managed the TARGET Protein Trial.
Matt commenced his PhD in July 2022 and is anticipated to complete this by the end of 2025. The focus of Matt’s doctoral research is to evaluate enteral protein delivery and protein metabolism in the critically ill.
Twitter: @msummo2

Adam Deane
Once he appreciated that being both scared of short pitched bowling and having a weakness against the swinging ball outside off-stump were major impediments to his dream of batting first drop for the Australian cricket team, Adam transitioned his career aspirations to medicine.
He currently pays the mortgage with employment as Staff Specialist, Head of Intensive Care Unit Research, and Deputy Director Intensive Care Unit at The Royal Melbourne Hospital. His academic appointments include Professorial Fellow in Intensive Care and Deputy Director of the Department of Critical Care Medicine at the University of Melbourne. From an earlier age, Adam developed a passion for frozen milk-based foods that stimulate sweet taste receptors. He continues to enjoy
following this passion whenever possible.
Twitter: @MelbourneICU
Editorialists & Panellists

John Myburgh
Professor John A Myburgh AO, is Professor of Intensive Care Medicine, University of New South Wales, Sydney; Director of the Professoriate and Immediate Past-Director of Critical Care Program at the George Institute for Global Health; Senior Intensive Care Physician at the St George Hospital, Sydney He holds a Leadership Fellowship from the National Health and Medical Research Council.
He has worked continuously as an Intensive Care Physician since 1988. He is an internationally recognised clinical researcher and has led the development and co-ordination of over 75 pivotal clinical trials in Intensive Care Medicine.
He has received over A$98M in research grant funding, published over 350 research publications and delivered over 400 presentations at national and international scientific meetings.
He is a Foundation Member and Past-Chairman of the Australian and New Zealand Intensive Care Society Clinical Trials Group, Foundation Member of the Australian and New Zealand Intensive Care Research Centre, Past-President of the College of Intensive Care Medicine and past-Secretary General of World Federation of Societies of Intensive and Critical Care Medicine.
More importantly, he is a dedicated family person, rower, cook and average blues guitar player.

Arthur Kwizera
Arthur Kwizera is a Professor in Anaesthesia and Intensive Care at Makerere University College of Health Sciences and a staff intensivist at the Mulago National Referral Hospital Intensive care unit. He has a bachelor of medicine and surgery (MBChB) and Master of Medicine in Anaesthesia and critical care from Makerere University. He obtained further critical care training from university of British Columbia in Canada. He is part of international collaborations looking at acute care in resource-limited settings with particular emphasis on sepsis management and anaesthesia/intensive care education. He has authored/co-authored a number of publications in this field. His research is centered on epidemiology, pathophysiology and management of acute organ dysfunction and corresponding life support interventions in low resource settings. For this PhD fellowship his focus is on Acute Lung disease with a particular emphasis on Acute Respiratory Failure (ARF) and Acute Respiratory Distress Syndrome (ARDS). He has conducted some work on genomics of ARF, but now wants to further determine the microbiology of ARF/ARDS as well as explore novel low cost strategies to manage acute respiratory failure in the Ugandan (and African) acute care setting.
Twitter: @ArthurKwizera

Bodil Steen Rasmussen
Bodil Steen Rasmussen, MD, PhD is Professor of Anaesthesia and Intensive Care Medicine at Aalborg University Hospital and Aalborg University, Aalborg, Denmark. Her research programme focuses on critically ill adults acutely admitted to the intensive care unit and specifically patients with acute hypoxaemic respiratory failure.
Prof Rasmussen was the primary investigator of a large randomised clinical trial evaluating two oxygenation targets in patients with acute hypoxaemic respiratory failure, amended to include patients with severe SARS-CoV-2 pneumonia with long-term follow-up focusing on pulmonary dysfunction and cognitive impairment. Additionally, mechanistic studies looking at metabonomic changes in blood and exhaled breath condensate following oxygen exposure.

Kathy Rowan
Professor Kathy Rowan is the Director of the NIHR Health and Social Care Delivery Research Programme, Director of the Intensive Care National Audit & Research Centre (ICNARC), Honorary Professor at the London School of Hygiene & Tropical Medicine and Adjunct Professor (Research) at Monash University, Australia.
In 1994, following her PhD from the University of Oxford, Professor Rowan founded ICNARC, an independent, not-for-profit, scientific organisation to facilitate improvements in the structure, process, outcomes and experiences of critical care - for patients and for those who care for them. ICNARC manages a broad programme of clinical audit and clinical/health services research, nationally and internationally.
Professor Rowan was awarded the Humphry Davy Medal by the UK Royal College of Anaesthetists (2004), completed a Harkness Fellowship (2005), received the President’s Prize with honorary life membership of the UK Intensive Care Society (2019) and Officer of the Most Excellent Order of the British Empire (Queen’s Birthday Honours’ List 2021) for services to research and intensive care.
Twitter: @KathyRowan101

Fernando Zampieri
Dr Fernando Zampieri is an assistant professor at the Department of Critical Care Medicine in the University of Alberta, Edmonton, Canada. He is also affiliated with the Academic Research Institute, at the Albert Einstein Hospital in Sao Paulo, Brazil.
Fernando graduated at University of São Paulo, Brazil in 2010 and was awarded a PhD in Medical Sciences by University of São Paulo in 2017. He has acted as principal investigator of both large pragmatic clinical trials and observational studies in critical medicine, including the BASICS trial.
Twitter: @f_g_zampieri

Andrew Udy
Andrew is Head of Research at The Alfred ICU, and Deputy Director, Australian and New Zealand Intensive Care Research Centre - Monash University. His research interests include traumatic brain injury, sepsis, and ECMO.
He is passionate about supporting trainees/early-career clinician-scientists, and increasing diversity in clinical research. He is a proud product of Aotearoa New Zealand.

Claudio Sandroni
Claudio Sandroni is a professor of Intensive Care at the Catholic University School of Medicine and Consultant at Gemelli University Hospital in Rome, Italy. He is responsible for post-cardiac arrest management in a 19-bed ICU. As a researcher, he focuses on post-anoxic brain injury and post-resuscitation care. Within the International Liaison Committee on Resuscitation (ILCOR) Dr Sandroni participates in the continuous evidence evaluation process that ILCOR conducts to provide rapid dissemination of resuscitation science and timely revised treatment recommendations. Dr Sandroni is member of the Editorial Board of Intensive Care Medicine, Official ESICM Journal , and the Editorial Board of Resuscitation, Official Journal of the European Resuscitation Council (ERC). He has been a Fellow of ERC since 2011 and a Fellow of the American Heart Association since 2024. To date, Dr Sandroni has authored 225 publications, which have been cited 15,794 times. His h-index is 55

Ludhmila Hajjar
Full Professor of the Clinical Emergencies Department at the Faculty of Medicine of the University of São Paulo – FMUSP, Associate Professor at the Faculty of Medicine of the University of São Paulo – FMUSP, PhD in Sciences from the Faculty of Medicine of the University of São Paulo – FMUSP, Specialist in Emergency Medicine by ABRAMEDE, Specialist in Cardiology by the Brazilian Society of Cardiology, Specialist in Intensive Medicine by AMIB, and Graduate from the University of Brasília/DF. She is currently the Director of the Emergency Service at the Central Institute of the Clinics Hospital of FMUSP, Director of Cardio-Oncology at the Heart Institute of HCFMUSP, Coordinator of Cardio-Oncology at the Cancer Institute of the State of São Paulo – ICESP, Coordinator of the Postgraduate Program in Cardiology at FMUSP, Coordinator of Cardiology at Hospital Vila Nova Star, Coordinator of the Cardiological and Surgical ICUs at Hospital DF Star.

Roberta Petrucci
Roberta Petrucci is a paediatrician with expertise in clinical research and public health. For over 15 years, she has worked in humanitarian paediatrics with Médecins Sans Frontières, completing more than 20 field missions in emergency and unstable settings in Sub-Saharan Africa, Latin America, Middle East and Europe. She has served as a clinician, medical coordinator, and technical referent, focusing on paediatrics, neonatal care, malnutrition, and outbreak response.
From 2019 to 2024, she led the MSF International Paediatric Platform and coordinated the development of neonatal and paediatric clinical guidelines for humanitarian contexts

Angelique de Man
Dr Angelique de Man is an intensivist at Amsterdam UMC in the Netherlands. She has extensive experience in clinical and, since she is also a medical biologist, also in translational research. Her domains of expertise in research comprise hyperoxia, cardiac arrest, vitamin C and micronutrients in critical care setting.
She coordinated the O2-ICU trial, investigating low-normal vs high-normal PaO2 target in 400 critically ill patients with SIRS (JAMA 2021). She was coauthor to the micronutrient guidelines (doi: 10.1016/j.clnu.2022.02.015) and is currently leader of the micronutrients working group of the ESICM. Furthermore, she is a member of the ESPEN special interest group for micronutrients. This year, she finalized the VITaCCA trial, an RCT investigating the effect of 2 different doses (3 and 10 g per day) of intravenously administered vitamin C versus placebo in 270 post cardiac arrest patient. Results will be published in the second half of 2025. In addition, she is currently working on the development of intracellular measurements of micronutrients in collaboration with the Reinier de Graaf Laboratory in the Netherlands.

Jo McPeake
Jo McPeake is Professor of Nursing at the University of Cambridge and Cambridge University Hospital’s NHS Foundation Trust. With a background in acute and critical care nursing, Professor McPeake leads a programme of research dedicated to improving the outcomes of critically ill patients and their family members. Her programme of research has a particular focus on how social inequalities influence healthcare access and outcomes. Characteristically using mixed methods approaches, Professor McPeake has experience of evaluating complex healthcare interventions in the acute care environment.

Zudin Puthucheary
Zudin Puthucheary is a Professor of Intensive Care Medicine at the William Harvey Institute, Queen Mary, University of London, and a Consultant at the Royal London Hospital Adult Intensive Care Unit. He graduated from Nottingham University in 1997, and moved to London post MRCP in 2000. Following a 3-year stint in Sydney, he started his Respiratory training in Bristol, before completing his critical care training in London.
Zudin's research focusses on acquired functional disability and skeletal muscle physiology, and specifically the use of metabolic and exercise interventions to prevent and treat acute muscle wasting. He is a nationally elected Council member of the Intensive Care Society (UK) and was the inaugural chair of the UK National Post-Intensive Care Rehabilitation Collaborative, a multi-professional cross-disciplinary group focussing on rehabilitation and restitution of critical illness survivors. He is the Chief Investigator of the ASICS-II and ASICS-TBI trials, investigating the efficacy of ketogenic feeding in preventing muscle wasting and secondary brain injury.

Kenneth Baillie
Kenny Baillie is Professor of Experimental Medicine at the University of Edinburgh and Consultant in Intensive Care Medicine.
He graduated from the University of Edinburgh with a BSc(Hons) in Physiology in 1999 and MBChB in 2002. He completed basic training in medicine in Glasgow, and in anesthesia in Edinburgh. During this time he led a series of high altitude research projects in Bolivia, and founded a high-altitude research charity, Apex. He was appointed as a clinical lecturer on the ECAT (Edinburgh Clinical Academic Track) at the University of Edinburgh in 2008, and completed a Wellcome Trust-funded PhD in statistical genetics in 2012. He was awarded a Wellcome-Beit Prize Intermediate Clinical Fellowship in 2013. He led a global consensus on harmonisation of research studies in outbreaks for the International Severe Acute Respiratory Infection Consortium (ISARIC), and worked with WHO on H1N1 influenza, MERS, and Ebola. After completing clinical training in 2014 he worked as a visiting scientist at the Broad Institute of Harvard and MIT, before returning to the Roslin Institute, University of Edinburgh to establish a research program in translational applications of genomics in critical care medicine. He works as a consultant in the intensive care unit at the Royal Infirmary, Edinburgh. During the Covid outbreak in 2020-21, he led the UK-wide GenOMICC and ISARIC4C studies, and contributed to the design and delivery of the RECOVERY trial. He discovered new biological mechanisms underlying critical illness in Covid, and contributed to the discovery of effective drug treatments to reduce mortality.
He leads a research programme in translational genomics - using genetic signals from critically ill patients to identify both the targets for drug therapy, and the groups of patients likely to benefit most from any treatment, and testing those therapeutic ideas in highly-efficient model systems.

Niall Ferguson
Prof. Niall Ferguson is Professor in the Interdepartmental Division of Critical Care Medicine, Department of Medicine, at the University of Toronto, with cross-appointments in the Department of Physiology and the Institute of Health Policy, Management and Evaluation. He is a practicing Intensivist and Clinician-Scientist at the University Health Network and is the Medical Director of the Toronto General Hospital Medical-Surgical ICU. He is a Senior Scientist in the Toronto General Research Institute and Director of the Toronto General Hospital Clinical Research Unit.
At a provincial level, Dr. Ferguson is Deputy chair of the Ontario Critical Care Command Centre. Dr. Ferguson’s research, which is supported by national and international peer-reviewed grants, investigates treatments for patients with acute hypoxemic respiratory failure with a focus on clinical trials in mechanical ventilation and extra-corporeal life support. He has published more than 300 papers listed on PubMed and his H-index is over 90. Dr. Ferguson is the Chair for Critical Care Canada Forum, Canada’s national critical care conference. He is a frequent invited speaker at national and international meetings, having given over 400 such talks.

Bronwen Connolly
Dr Bronwen Connolly is a critical care physiotherapist, and Senior Lecturer in Critical Care at Queen’s University Belfast, UK. The recipient of three previous NIHR Fellowships (Doctoral, Postdoctoral, Clinical Trials), her research interests focus on acute respiratory and rehabilitation physiotherapy, the recovery, long-term outcome, and survivorship of post critical illness patients, and clinical trial methodology around complex rehabilitation interventions. Her current work includes leading a multiprofessional team developing a randomized controlled trial investigating the effectiveness of mucoactive drugs in acute respiratory failure, and the development of a core outcome set for trials of physical rehabilitation in critical illness. Bronwen is involved with a number of major national and international research organisations including the NIHR Critical Care Specialty Group, the UK Critical Care Research Group, and the International Forum for Acute Care Trialists.
Twitter: @bronwenconnolly

Peter McGuigan
Dr. Peter McGuigan is a Consultant in Intensive Care Medicine and Anaesthesia at the Regional Intensive Care Unit at the Royal Victoria Hospital Belfast. Peter is an early career researcher in the field of critical care medicine. Peter is co National Investigator for the STEPCARE cardiac arrest trial in the UK and Ireland. Peter won the ICC-CTNS Early career researcher Seed funding award (ECR-SFA) in 2023. His current research interests include neuro-monitoring and phenotypes in cardiac arrest.
Twitter: @Pete_McGuigan

Jon Silversides
Jon undertook specialty training in anaesthesia, and critical care, gaining FRCA, MRCP, EDIC and FFICM qualifications. He completed a fellowship in critical care at the University of Toronto, Canada before being appointed as a Consultant in Critical Care and Anaesthesia in the Belfast Health and Social Care Trust in 2013.
Jon completed his PhD in 2019, which included running the ‘Role of Active Deresuscitation After Resuscitation-2’ randomised trial, and was appointed Clinical Senior Lecturer in Critical Care at Queen’s University Belfast in 2021. He leads clinical trials in both critical care and perioperative medicine, including a ‘conservative fluid therapy’ intervention arm of the NIHR-funded SepTIC trial, and as Chief Investigator for SINFONIA, a 2500-patient NIHR-funded randomised trial comparing Sugammadex with Neostigmine for prevention of post-operative pulmonary complications after major surgery.
Twitter: @jon_silversides
Journal Editors

Darren Taichman
Darren Taichman, MD, PhD, MACP is a pulmonary and critical care physician who practices and teaches at the University of Pennsylvania. At Penn, he was Director of the intensive care unit and led research programs focused on critical care medicine and pulmonary vascular disease. Dr. Taichman’s editorial work began in 2007 at the Annals of Internal Medicine, where he was the Executive Editor as well as Vice President of the American College of Physicians, the largest medical specialty organization in the United States. He served as Secretary of the International Committee of Medical Journal Editors from 2014 – 2021. In 2020, Dr. Taichman was appointed Deputy Editor and Online Editor of the New England Journal of Medicine, as well as the Executive Strategy Editor for the NEJM Group. He continues to teach and see patients at the University of Pennsylvania, with a specific focus on the treatment of pulmonary hypertension.

Christopher Seymour
Dr. Seymour is an Associate Professor in the Departments of Critical Care, Emergency Medicine, and Clinical and Translational Science at the University of Pittsburgh School of Medicine. Over the past 10 years, his research program has focused on clinical and translational studies involving sepsis, biomarkers, and large electronic health record databases. Dr. Seymour completed his NIGMS Career Development Award (K23), mentored by Dr. Derek Angus, titled “Prehospital identification of high-risk sepsis.” This successful award led to funding of a NIH/NIGMS R35 ESI-Merit Investigator Research Award, “Sepsis endotypes during emergency care.” He is Director of the Clinical and Translational Science Program in the Department of Critical Care Medicine, member of the International Sepsis Forum (ISF), and Associate Editor for Critical Care at JAMA. His research has been published in the New England Journal of Medicine, JAMA, and The Lancet, among others.
Twitter: @seymoc
Statisticians

Marion Campbell
Marion Campbell is Vice-Principal (Research) for the University of Aberdeen and Professor of Health Services Research in the Health Services Research Unit (HSRU). Marion is a medical statistician and clinical trialist. Her main research interests are in the design, conduct and analysis of clinical trials, especially complex trial design and the design and conduct of surgical and device trials. She has published widely on clinical trials methodology, including on cluster randomised trials, design of trials of non-pharmacological interventions, pragmatic trials and trials reporting. She has served on many national and international funding agencies and committees and is an elected Fellow of the Royal Society of Edinburgh, the Faculty of Public Health and the International Society for Clinical Trials.
Marion graduated with an honours degree in Statistics from the University of Aberdeen and subsequently gained an MSc in Statistics and PhD in Public Health. Following early career appointments within the National Health Service in the fields of Operational Research and Statistics of Medical Audit, she joined the Health Services Research Unit in 1993. She became Director of the Unit in 2007 - a position she held until the end of 2015, when she became Dean of Research for Life Sciences and Medicine. She took up the role of Vice-Principal (Research) in October 2017. HSRU remains her academic base.
Twitter: @MarionKCampbell

Victoria Cornelius
Victoria Cornelius is a Professor in Medical Statistics and Trial Methodology and Director of Imperial Clinical Trials Unit. Her work in trials includes evaluating drug and complex interventions developing approaches that promote statistical efficiency in both Bayesian and frequentist frameworks. Her statistical methods research is in the use of time-to-event signal detection methods to identify adverse drug reactions, and co-leads the NIHR MRC TMRP specialist research group to improve the analysis of harm outcomes in randomised controlled trials.
Twitter: @VR_Cornelius

Ranjit Lall
Prof Lall provides oversight to the Statistics Group at the Warwick Clinical Trials Unit and leads on the design and analysis of an internationally competitive and sustainable portfolio of clinical trials in the area of complex interventions (rehabilitation and accident and emergency care). She has responsibility, with the Director, for the strategic management and development of the WCTU, gaining world-wide recognition for excellence in the conduct of randomized controlled trials. Her contributions towards this aim have included taking the lead in delivering the Conference of Clinical Trials of Complex Interventions and Multi-components (April 2015, Warwick) and taking the lead on delivering the Workshop in the Design and Analysis of Complex Interventions (at the International Clinical Trials Methodology Conference, Glasgow, 2015).
Prof Lall was part of the groundbreaking PARAMEDIC2 trial team, which investigated adrenaline in patients with out-of-hospital cardiac arrest.

David Harrison
Prof David Harrison graduated from the University of Cambridge with an MA in mathematics and a PhD in mathematical modelling of disease progression. He has worked for ICNARC since 2002. David is a Fellow of the Royal Statistical Society and an Honorary Professor in the Medical Statistics Unit of the London School of Hygiene & Tropical Medicine.
Twitter: @DavidHarrison80

Monica Taljaard
Monica Taljaard is a Senior Scientist in the Methodological and Implementation Research Program at the Ottawa Hospital Research Institute (OHRI) and Full Professor in the School of Epidemiology and Public Health at the University of Ottawa. Her main research interests are in the design, analysis and ethics of pragmatic and cluster randomized trials. As a methodologist with the Ottawa Methods Centre, she works with clinicians and researchers from a variety of backgrounds in the design and analysis of their studies including clinical trials and observational studies. She has published over 500 peer reviewed journal articles and helped secure >$190 million in peer-reviewed research grants, including >$60M as principal or co-principal investigator. She is Deputy Editor of Clinical Trials: Journal of the Society for Clinical Trials.

Elizabeth George
Dr. Elizabeth George is a statistician and researcher with 15 years of experience working on clinical trials focused on acutely ill children presenting to hospitals in Africa. She has contributed to award-winning large trials that have challenged the status quo, led to changes in guidelines, and provided crucial evidence supporting existing guidelines. These trials have sparked numerous global debates and discussions. Her work has included trials on fluid resuscitation for pediatric shock, blood transfusion volumes for severe anemia, antibiotics for severe malaria and bacterial co-infection, and fluids for children with gastroenteritis with or without severe malnutrition.
Dr. George leads subsequent analyses, publications, and dissemination projects from these trials, developing analysis plans and collaborating closely with colleagues. She has also served as a trial statistician for smaller trials that have clarified underlying mechanisms and helped inform future research.
Dr. George is passionate about conducting high-quality clinical trials to answer critical questions and provide evidence for treatment guidelines for children presenting to hospitals in Africa.
Twitter: @lcgeorge13